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PLOS One 16 , e0252520 (2021)

Vitamin B12 deficiency can occur less frequently as a result of nutritional habits (strict vegans, breastfed infants born to vegan mothers with reduced dietary intake of animal products), drug interference (metformin, proton pump inhibitors, drug-affected purine, and pyrimidine synthesis), inherited disorders affecting intrinsic factor (IF) and other inherited disorders including methylmalonic acidemia and transcobalamin II deficiency nitrous oxide abuse, Diphyllobothrium latum infection, and pancreatic insufficiency.[] Metformin is considered a cornerstone in the treatment of diabetes and is the most frequently prescribed first-line therapy for individuals with type 2 diabetes

The Institute of Medicine recommends people over 50 consume supplemental sources of vitamin B12 either through fortification or supplementation

A comparison of both molecules will help you decide which might help your weight loss goals

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