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In general, the figures show pooled data from independent experiments

Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior

aminopropylation SAMe is decarboxylated to produce polyamines which promote DNA and protein synthesis, necessary for normal hepatocyte growth and repair

Cisplatin is a platinum-based chemotherapy drug that was approved by the FDA in 1978 despite its harsh side effects of inducing organ damage (including the liver and kidneys) [299], through oxidative metabolism via CYP2E1 and CYP4A11 [300]