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This pivotal action relieves Bcl2's inhibition of the mitochondrial apoptosis pathway, thereby promoting the initiation of intrinsic apoptosis programmes in cancer cells and ultimately effectively suppressing tumour cell proliferation [89]

doi: 10.1517/14656566.2014.972935 119 YanaiHMasuiYKatsuyamaHAdachiHKawaguchiAHakoshimaMet al

Furthermore, the expression changes of other integrin subtypes in these cells vary, suggesting that the integrin profile may be specific to each cell line (Juengel et al., 2016a)

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It would be interesting to determine whether intranasal delivery of mRNA vaccines can promote T RM cells and protection in the lung