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184,185 The pathophysiology of DRPN involves ischemic injury due to microvasculitis leading to nerve fiber ischemia and immune-mediated mechanisms, as evidenced by inflammatory infiltrates in nerve biopsies

Once supplementation stops, B12 levels typically return to the normal range within a few months

Potential Side Effects and Safety Considerations Vitamin B12 injections are usually safe but can have side effects

It is noteworthy that the volunteers included in this study had mild COVID-19 in 2021, prior to the emergence of the SARS-CoV-2 Omicron variant and when the Brazilian population had not completed the full COVID-19 vaccination schedule