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Gao Z, Wang G, Chen Y et al (2024) Total flavonoids of Astragalus membranaceus protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice by inhibiting ferroptosis through SLC7A11/GPX-4 signaling pathway

The fact that a compound is popular does not make it safe or effective, and loosening restrictions without requiring adequate clinical data would set a dangerous precedent

111 , 112 eFT226 is also being studied and is currently the subject of a major phase 12 clinical trial evaluating the drug against advanced stage solid tumors, including NSCLC (ClinicalTrials.gov: NCT04092673)

N Engl J Med 2006