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Similarly, DNMT1 knockdown promoted senescence and decreased differentiation potentials of MSCs at early passage, whereas DNMT1 overexpression has the opposite effect at late-passage MSCs, suggesting that RB preserves the proliferation and differentiation potential of MSCs by upregulating DNMT1 [65]

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Involvement of adiponectin-SIRT1-AMPK signaling in the protective action of rosiglitazone against alcoholic fatty liver in mice

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