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Description
As recently shown in a murine model, deletion of Met led to enhanced growth and metastasis of transplanted or endogenously induced tumors by reduced neutrophil infiltration (73)
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PMID 8810901
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Mitophagy depends on lipid oxidation, which is under physiological conditions controlled by GPX4
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10.1038/tp.2013.91 [DOI] [PMC free article] [PubMed] [Google Scholar] Ponzetto C., Bardelli A., Zhen Z., Maina F., dalla Zonca P., Giordano S., et al
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Lysosomal acid lipase, CSF1R, and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cells
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