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OR internalization The number of active OR at the cell surface is regulated by two processes: endocytosis and export of neosynthesized receptors

Among natural permeation enhancers, terpenes such as -bisabolol that have gained attention due to their ability to interact with mucosal lipids, enhancing drug permeability without affecting tissue integrity, as demonstrated in vitro studies using porcine mucosa in small drug molecules [95]

Chronic elevation at 12% significantly increases the risk of long-term microvascular complications , such as retinopathy, nephropathy, and neuropathy

Cancer Cell 38 , 872890.e6 (2020)

& Fowler, C