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Description
DJ-1 is an oxidative stress sensor that prevents neuronal death induced by oxidative stress and inhibits the aggregation of -synuclein via its chaperone activity

Daran-Lapujade et al, 2007

Make sure you make it gradually and step-by-step

Experimental data have suggested a role for GSH as a neuromodulator

These effects were dependent on UBE3As ligase activity and were observed both with and without oncogene expression, indicating an endogenous role for UBE3A in clock regulation
