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122 , 123 It is of interest that data from the USA Kernicterus Registry from 1992 to 2004 indicate that over 30% of kernicterus cases are associated with G6PD deficiency

The inhibition rate goes along with the increased dose of 1D228 and Tepotinib, the IC 50 of 1D228 were 4.3 nM or 1 nM respectively on MHCC97H or MKN45, which is lower than the reference compound Tepotinib which is 13 nM or 1.65 nM

These bioactive compounds exhibit various beneficial properties, such as antioxidants, anti-inflammatory, antibacterial, and antidiabetic activities, offering potential for use in functional foods and therapeutic applications

And I think just having more research on these things so that we know how is this going to work, because sometimes the marketing gets ahead of the actual evidence or, you know, effects of things

Clinical manifestations encompass memory loss, cognitive impairment, personality changes, and in severe cases, hallucinations and seizures (74)