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Description
Both methionine and homocysteine accumulate within cells and bodily fluids of individuals with homocysteinuria with the concomitant result that cysteine biosynthesis is impaired, hence reducing the availability of this amino acid

HT-1080 p53 KO : siControl, 0.15 10 5

As a result, a great number of studies have investigated the direct generation of LA from starchy materials by using either natural amylolytic LAB or genetically engineered amylase-producing LAB [83]

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Likelihood score: A (well known cause of clinically apparent liver injury)
