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154 WangM.MaoC.OuyangL.LiuY.LaiW.LiuN.et al (2019c)

A higher TSH in relation to serum free T4 is seen during longterm amiodarone therapy, perhaps because this drug, or its active metabolite, desethylamiodarone, acts as an antagonist at thyroid hormone receptors

Metabolism involves a process of biotransformation in which the chemical structure of the xenobiotic is changed

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