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The essential fatty acids, linoleic (C18:2n-6) and -linolenic acid (C18:3n-3), cannot be synthesized in the mammalian organism and must therefore be provided by the diet

Humans have not been consuming these things for very long so we still don't know the long-term ramifications

177 Other conditions with similar clinical features include thyroid disease, hyperprolactinemia (high levels of the hormone prolactin), an androgen-producing tumor of the ovary or adrenal gland, and non-classical congenital adrenal hyperplasia (NC-CAH), which causes adrenal steroid 21-hydroxylase deficiency

The lesions occurred in the brain (including intracerebral and intraventricular hemorrhage), heart (severe arrhythmias, congestion, and endocardial infarction), lungs (hemorrhage), and congestion in the liver, kidney, and gastrointestinal lesions