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The peptide, humanin, was ultimately traced to a tiny snippet of mitochondrial DNApart of the ninety-eight per cent of the human genome that had long been dismissed as junk DNA. Cohens work helped reveal that, in the three-billion-letter book that is our genome, even obscure one-liners can be an important part of the story

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Actin staining was then performed with pre-conjugated Phalloidin-Alexa Fluor 488 (Cytoskeleton, PHDG1A) diluted 1:140 in Antibody Diluent Reagent Solution (Invitrogen, 003218) for 30 min in the dark at room temperature

The anti-inflammatory effect of the probiotic Clostridium butyricum is the result of the induction of TGF- signaling in DC, which, in turn, induces Treg cells generation [34]