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PLC-1 can regulate the phosphorylation of ERK and serine/threonine kinase (AKT), and then activate phosphoinositide-3 kinase (PI3K)/AKT signal to induce CCA cells to undergo EMT

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qRT-PCR RNA for qRT-PCR was extracted with TRIzol according to the manufacturers instructions from synchronous worms 26 h after L1

doi: 10.1073/pnas.0506654102 57 CivelekM.HagopianR.PanC.CheN.YangW