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[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Viader A, Sasaki Y, Kim S, Strickland A, Workman CS, Yang K, et al

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How things go bad As we get older, our brain chemistry and energy metabolism changes.[vii] Nerve growth factor in the brain declines Acetyl-L-Carnitine levels decline Acetylcholine levels decline Mitochondria loses efficiency All of these age-related changes are contributing factors to cognitive impairment and the neurodegenerative diseases of aging, including Alzheimers and dementia