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Multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19
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Discussion In this work, we identified parallel biosynthetic pathways that control fatty acid desaturation via NHR-49/PPAR, (i) a pathway dependent on microbiota-derived cyclopropane lipids, which are converted endogenously into the -cyclopropane 11-carbon fatty acid, becyp#1, and (ii) a fully endogenous pathway that requires the HGT-derived methyltransferase FCMT-1 for biosynthesis of the -methyl-branched 11-carbon fatty acid, bemeth#1 (Fig
