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Combining antiangiogenic agents, such as saikosaponin b2 which targets the VEGF/ERK/HIF-1 pathway, with immunotherapy enhances treatment efficacy

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Nonetheless, this multiomics study elucidates an adipose-vessel crosstalk involving adipocyte-derived miR-30e-5p and its targeted SLC7A11 in vascular ECs

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RNA expression analysis of the Lynch syndrome-CRC patients (II.2) tumour predicts the presence of tumour infiltrating lymphocytes (TILs) and myeloid cells Having determined the immunogenic potential of three peptides in the Lynch syndrome patient, we analyzed the tumour transcriptome to predict the type and nature of tumour infiltrating immune cells