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Stacking amplifies side-effect risk with no proven added benefit

Natalizumab is a recombinant humanized IgG4k monoclonal antibody

Primary antibody for PECAM1 first and then Alexa Fluor TM 488 detection antibody (green) were used to label the vessels of blood
Unlike what is observed in neurodegenerative diseases, psychiatric diseases do not have prominent characteristics of neuronal loss (reviewed by (Duman et al., 2016
