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Description

Metabolites derived from cytochrome P450-dependent DIC oxidation (2,5-quinone imines and 4,5-hydroxy-diclofenac) can enhance reactive oxygen species (ROS) production by inducing redox imbalance and mitochondrial dysfunction

PET MPs were detected in all cardiac tissues examined (pericardium, epicardial adipose tissue, pericardial adipose tissue, myocardium, and left atrial appendage), with the highest prevalence in the pericardium (96%) (mMPs size range 20469 m)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 31.PubChem [Internet] Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information