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Your body produces thousands of peptides naturally, and they play essential roles in nearly every biological function, including: Tissue repair and wound healing Collagen and elastin production Immune response and inflammation Hormone signaling Cell communication and regeneration Think of peptides as messengers

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However, sustained ROS overload skews this protective mechanism toward dysfunction

Ebselen was found to increase the expression of GPX1 in SGNs after peroxynitrite damage, which is consistent with the reports that ebselen can increase the expression of GPX1 in cochlea after electrical stimulation ( gpx1 / mice leads to the aggravated SGN injury (cell loss and apoptosis) induced by peroxynitrite, although it might cause no effect on SGN development as SGNs presented normal morphology and cell number in gpx1 -deficient mice

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