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doi: 10.1155/2019/9084643
The enormous selective advantage of red blood cells with normal hemoglobin or anti-sickling hemoglobin predicts that genetic modification of a proportion of HSCs (estimated 1020%) may suffice as a one-off treatment (ClincialTrials.gov Identifier: NCT02963064)
doi: 10.1016/0196-9781(94)90152-x
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