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Students t test was used to determine statistical differences between two experimental groups depending on the genotype, experimental conditions and the disease group

While the clinical phenotype observed in Papillon-Lefvre syndrome (PLS) necessitates careful monitoring of skin and periodontal health during DPP1 inhibition therapy, clinical trials have shown these adverse events occur at low frequencies (1%4%) and are predominantly mild to moderate in severity

Intended for licensed compounding pharmacists and healthcare professionals

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