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International Journal of Pharmaceutical Research and Allied Sciences 8(32019):212224 Ali F, Smith CH, Mahil SK (2023) Spesolimab in treating generalized pustular psoriasis: a critically appraised research paper

So, future randomized control trial needs to address this potential confounding factor in evaluating more realized vitamin B12 effect

Complete another 10-day cycle, and increase again by 1mg per dose

are at least in part caused by B12 deficiency