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Biased agonism A signalling response determined by the conformation of the drugreceptoreffector complex that engages only a subset of cellular effectors

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Occasionally, signs of acute toxicity may be absent for 1248 hours following administration, after which a critical phase may develop, characterised by pulmonary oedema, vasomotor collapse, cyanosis, acute hepatic failure, coma, and death of the animal

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Published online 2016 Apr 19