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Arachidonic acid lipoxygenase 15 (ALOX15), acyl-coa synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) are key enzymes in lipid metabolism and are required for ferroptosis

Interleukin-1 alpha (IL-1) expression initiates a cascade leading to a proinflammatory state that activates nuclear factor-kappa-B (NF- B) and promotes epithelialmesenchymal transition, thereby facilitating tumor metastasis
doi: 10.3390/nu11051189 116 MichalopoulosI.MathioudakisD.PremetisI.MichalakidiS.PapadopoulouK.LyberatosG

PMID: 249 MastrantoniLGarufiGGiordanoGMaliziolaNDi MonteEArcuriGet al

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