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2.2.1 Immune microenvironment remodeling: TAMs polarization and TLR4 signaling activation SF constructs an immunosuppressive microenvironment to directly promote lung cancer progression by regulating the function of TAMs and downstream signaling pathways

Approximately 20% of CRC patients will develop metastases, resulting in a less than 5-year survival rate of only 14% with conventional treatment (Rumpold et al., 2020)

The depletion of glutathione in peripheral blood mononuclear cells and red blood cells has been observed in tuberculosis patients compared to a healthy control [98]

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Currently, intranasal PYY 3-36 is the subject of long-term phase II studies
