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Although Minocycline inhibits microglial activation (Wu et al., 2002), other studies have shown it to significantly exacerbate MPTP-induced damage to DA neurons in vitro and in vivo (Yang et al., 2003)

Gl utathione and immune function
Courchesne E, Pierce K, Schumann CM, Redcay E, Buckwalter JA, Kennedy DP, et al

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Such results support the concept of a co-ordination of regulatory pathways through cross-talk between thioredoxin and GSH homeostasis
