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Description
Changes in the gut microbiome may significantly impact ME/CFS, potentially due to increased gut permeability that allows bacteria to enter the body, or through fermentation products affecting cells and immune responses, exacerbating cognitive and physical impairment in ME/CFS patients
"Stable gastric pentadecapeptide BPC 157-NO-system relation." Current Pharmaceutical Design

Specifically, the CTLD4 domain can recognize specific components, thereby mediating cellular immune regulation (213)

Likewise, B-cell activating factor (BAFF) secreted by mDCs induces the activation and differentiation of B cells
& Insel, P
