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This is crucial for injury recovery because new blood vessels deliver oxygen and nutrients to the affected areas, promoting faster healing
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Physical activity of the skeletal muscle is directly correlated with O 2 consumption, therefore, more intense is the exercise greater is the production of ROS/RNS
In several studies, researchers demonstrated that doxycycline inhibited matrix MMP activity, which significantly reduced GL shedding and, therefore, leukocyte adhesion to EnCs in response to inflammatory and ischemic stimuli [5, 25, 183]
