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Despite these efforts, the clinical outcomes using these CB2 ligands have shown limited effectiveness [35]
LaVaute T, Smith S, Cooperman S, et al
Journal of Crohns and Colitis 7 e197e
Hofstetter TB Formation of N-Nitrosodimethylamine during Chloramination of Secondary and Tertiary Amines: Role of Molecular Oxygen and Radical Intermediates
For instance, small interfering RNA (siRNA) strategies can selectively inhibit target mRNA, minimizing off-target impacts
