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However, the placenta is armed with antioxidant defences, including the selenium-dependent glutathione peroxidases, thioredoxin reductases, selenoprotein-P, and copper/zinc and manganese superoxide dismutases (Cu/Zn and Mn SODs) (Figure 2), which protect the placenta from any undue harm [2124]

The endocannabinoid 2-arachidonoylglycerol and dual ABHD6/MAGL enzyme inhibitors display neuroprotective and anti-inflammatory actions in the in vivo retinal model of AMPA excitotoxicity

Annotation parameters for APAP metabolites according to Schymanski et al

Biomed Pharmacother 89:10611066 Nooijer AH, Pickkers P, Netea MG, Kox M (2023) Inflammatory biomarkers to predict the prognosis of acute bacterial and viral infections

GSH is a soft nucleophile (i.e., the sulfur is of low electronegativity and high polarizability and is easily oxidized) and preferentially reacts with soft electrophiles (i.e., compounds that contain an acceptor atom with high polarizability, low electronegativity, and often unshared p or d valence electrons)