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In vivo , in a type IV collagenase-induced ICH mouse model, oral BC administration (20 mg/kg) for three consecutive days alleviated motor deficits and brain injury, reduced iron deposition in perihematomal brain tissue, and exerted anti-ferroptotic effects by upregulating the expression of GPX4 and SLC7A11 (227)
Up to now AIIRA have not been extensively used in children with diabetes, but more evidence of the efficiency and safety must be available before AIIRAs can become an obvious choice for the treatment of diabetic nephropathy and hypertension in children and adolescents in the near future

The authors showed that SFN treatment improved cognitive and locomotor deficits evaluated by Morris water maze and open field test

Outcome measures including the Revised Fibromyalgia Impact Questionnaire (FIQR), Hospital Anxiety and Depression Scale (HADS), 12-item Short-Form health survey (SF-12), and pain Visual Analog Scale (pain-VAS) were fulfilled by patients before and after the treatment

[DOI] [PubMed] [Google Scholar] 60.Frentzas S., Simoneau E., Bridgeman V.L., Vermeulen P.B., Foo S., Kostaras E., Nathan M., Wotherspoon A., Gao Z.H., Shi Y., et al