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All human AML cell lines, HL-60 (ACC 3), MOLM-13 (ACC 554), MV4-11(ACC 102), THP-1 (ACC 16), KG-1 (ACC 14), PL-21 (ACC 536) were purchased from DSMZ and validated using STR profiling

223 Dynamin-related protein 1 promotes fragmented mitochondrial puncta formation in latent brain metastatic cells, leading to a shift towards fatty acid oxidation (FAO) metabolism that maintains redox homeostasis and survival of tumor cells within the brain microenvironment

In vivo imaging experiments showed that PTX-CHO-RVG15-Lipo significantly increased the accumulation of PTX in the brain and promoted its penetration into C6luc glioma

Although the final outcomes of these two processes are the same, if senescence begins, it ensures that the lesion is efficiently removed via immunosurveillance, whereas, if apoptosis begins, it destroys the damaged cells without initiating an immune response [195]

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