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Description
Over the last 10 years, wet AMD has seen a revolution in treatment modalities and patient outcomes

This direct enzyme damage is compounded by the inactivation of crucial detoxification systems, such as glyoxalase I (GLOI), leading to the toxic accumulation of methylglyoxal and advanced glycation end products (AGEs) that damage proteins and nucleic acids [9193]

doi: 10.1074/jbc.RA118.004202 104 KimuraT.JainA.ChoiS

(Torbey, 2019) Mechanism of action : Stimulates inhibitory GABA-A receptors

Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations
