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By simultaneously engaging a target protein and an E3 ubiquitin ligase, PROTACs trigger selective protein degradation and enable precise removal of disease-driving proteins

Coelho, Andresa A

CACT acetylation mechanism is in line with a dynamic post-translational protein control that could undergo an on/off switch induced by deacetylation/acetylation linked to the availability of acetyl-CoA 57

Transcriptional impact of dietary methionine restriction on systemic inflammation: relevance to biomarkers of metabolic disease during aging
