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The formed chloramines have also been implicated in mediating cytotoxicity to a broad array of microorganisms [223]

Clinical translation and emerging therapeutic applications of intranasal drug delivery systems In recent years, there has been a notable increase in the clinical translation of advanced intranasal delivery technologies, particularly those designed to overcome limitations associated with conventional nasal sprays, such as anterior deposition, post-nasal drip, and inconsistent dosing due to nasal valve obstruction

Serum samples were collected from confirmed LNB patients before and after treatment, with post-treatment samples serving as controls

Notably, Lactobacillus helveticus Lafti L10 has demonstrated significant enhancement of immune status in elite athletes when administered at a dosage of 2 10 10 CFU daily for a period of 14 weeks (Michalickova et al

Jan 2021;15(1):8-14