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are known to produce low molecular weight organic acids (LMWOAs) such as oxalate, citrate, malate, formate, acetate, and succinate, which contribute to pH modulation (145, 146)

The mechanisms by which mitochondrial complex III controls Treg cell suppressive function are not fully understood but may involve l-2HG, which inhibits -KGDDs including TET enzymes responsible for DNA demethylation

Despite promising findings, research on exercise interventions targeting ferroptosis in NAFLD is still in its infancy, with many unanswered questions and challenges

The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains

M., Guo Z., Ye R., Jha R., Grifno G