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It has been found that patients with chronic malabsorption and selective IgA deficiency, who are deficient in vitamin E and selenium, develop PM when treated with iron dextran, which is believed to be related to lipid peroxidation induced by free radicals activated by free iron [235]

They reported significantly increased P450 aromatase (CYP19A1) expression in endometriosis patients: 32.4% of the endometriosis patients presented moderate expression, and 67.6% presented strong expression, with no cases of negative or weak expression observed