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Withdrawal rates due to adverse effects serve as a practical measure of real-world tolerability, as they reflect whether side effects are bothersome enough to outweigh potential benefits

Telogen Effluvium Stress, illness, hormonal changes, and nutritional deficiencies can trigger excessive hair shedding by pushing many follicles into telogen simultaneously

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Some researchers report stable results up to 45 or 60 days, but 28 days is the window within which potency is most reliably maintained