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doi: 10.7150/thno.38147

Shiroiwa T, Fukuda T, Shimozuma K, et al
Development of S-Substituted Thioisothioureas as Efficient Hydropersulfide Precursors

The mode of action of this novel drug involves inhibiting inositol acyltransferase Gwt1, an enzyme in the GPI anchor biosynthesis pathway

Why Conventional Wisdom Fails Most patients with chronic kidney disease are told the same story: CKD is a slow, inevitable decline
