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Sinauer Associates

Ipamorelin's human data is limited to two published pharmacokinetic/pharmacodynamic studies: a 1999 PK/PD study (PMID: 10496658) that documented dose-response relationships and peak GH at 30-40 minutes post-injection in human volunteers, and a completed Phase II clinical trial for postoperative ileus (NCT00672074), after which ipamorelin's development for this indication was discontinued without approval

Our analysis revealed negative correlations between GLO-1 expression and several treatments, including omacetaxine, niclosamide, methotrexate, marinopyrole A, aporina, YM-155, STF-31, KX2-391, KPT185, GMX-1778, CAY-10618, and BI-2536 ( Figure 7 )
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