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B12 deficiency can lead to anemia and neurological disorders

10.1016/j.bbapap.2015.09.006 156

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Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages

(Source 13) While there is still more to learn, animal studies on yellow food dyes (including Yellow 6) decreased glutathione-s-transferase enzymes as a marker of oxidative stress