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Figure 1 3.1 Autoimmune and inflammatory responses in GD increase the risk of depression GD is a common autoimmune disease in which excessive production of stimulatory autoantibodies disrupts critical physiological processes inside and outside the thyroid gland in GD, resulting in cellular and humoral immune disorders ( Cytokines play an important role in autoimmune responses and are often used as indicators to predict the occurrence and progression of diseases ( 3.1.1 Disrupting neurotransmitter metabolism Neurotransmitters are vital chemicals that transmit information between neurons or neurons and effectors