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Role of hypercholesterolemia in osteoarthritis development

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ET-1 and IL-18 respectively

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Current reliance on preclinical evidence underscores the urgent need for rigorous clinical trials

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Polo-like kinase (PLK) and creatine kinase (CK) are the main kinases promoting -syn phosphorylation [14], while PP2A is the main phosphatase promoting -syn dephosphorylation [15]

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We chose intranasal administration of UCT-MSC-EXs as we felt it delivered better efficacy than intravenous administration for crossing the BBB

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