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For example, ubiquitination of many GPCRs including PAR, histamine (H 1 or H 2 receptor), and prostaglandin EP 2 (EP 4 prostanoid receptor) activates p38 MAPK via a transforming growth factor- activated protein kinase 1binding protein (TAB)1-TAB2dependent pathway, which occurs through an interaction between TAB2 and K63-linked ubiquitin on the GPCR (Grimsey et al., 2018, 2019)
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Fiala, M
Some research suggests it may have potential benefits for wound healing and tissue repair
