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As cyst(e)inase should leave extracellular proteins untouched, the effectiveness of cyst(e)inase treatment against several cancers in vivo suggests that either macropinocytosis is not active in these cancers or that cysteine is not derived from protein catabolism at high enough rates to support cell survival [6]

Other reasons include: Peptides are found in literally every cell in the body

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Gastroenterology 2021;160:15701583.ArticlePubMed 12

[PubMed: 1411543] 98