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Expresin de melanina: los melanosomas son transferidos desde los melanocitos a los queratinocitos y se observa el color de la melanina en la mucosa ( 11 )

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They may recommend the initiation of sodium phenylacetate/sodium benzoate (ammonia scavengers) and L-arginine in an attempt to provide alternative methods for nitrogen excretion and override the OTC defect at the initial step of the urea cycle or to treat undifferentiated inborn errors of metabolism ( Figure 4 )

These findings suggest a substantial degree of central sensitization in cirrhosis, highlighting nociplastic pain as a crucial component of chronic pain in these patients (68, 81)