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Kidney Int Suppl 69:S93-106 Mercadal L, Coudert M, Vassault A, Pieroni L, Debure A, Ouziala M et al (2012) L-carnitine treatment in incident hemodialysis patients: the multicenter, randomized, double-blinded, placebo-controlled CARNIDIAL trial

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5 Mitochondrial metabolism, inflammatory tone and insulin resistance As mentioned above, LAC is an endogenous compound essential for -oxidation and is an emerging epigenetic modulator of glutamatergic function

[DOI] [PMC free article] [PubMed] [Google Scholar] 106.Janiri L, Falcone M, Persico A, Tempesta E

Mechanisms underlying the anti-wasting effect of L-carnitine supplementation under pathologic conditions: evidence from experimental and clinical studies