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While acute cuprizone intoxication in rodents has shown to lead to increased synaptic density in superficial cortical layers, in the subcortical area, such as the dorsal lateral geniculate nucleus, the contrary has been observed

In this context, large-scale, multi-center studies are needed to better understand the etiology and clinical course of AA

Some causes of B12 deficiency are: Pernicious Anemia Autoimmune Diseases Leaky Gut Syndrome Ulcerative Colitis, Crohns and Celiac Disease Small Intestinal Bacterial Overgrowth (SIBO) H Pylori Infection Prolonged Usage of Gastric Reflux meds Vegan and Vegetarian diets MTHFR gene mutations Bariatric Surgeries Excessive Alcohol Consumption B12 and the Methylation Cycle: Methylation is a critical process that happens trillions of times in every cell each minute

We added sulfanilamide to the homogenized tissue

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